Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9598039 | 1.00 | ADRB1 (0.68) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL19944672 | 0.92 | ADRB1 (0.73) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL18034999 | 0.87 | ADRB2 (0.68) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL15275621 | 0.86 | ADRB1 (0.66) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL11093561 | 0.86 | ADRB2 (0.66) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL7215333 | 0.86 | ADRB1 (0.66) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| Hydrochloric Acid SCHEMBL10607565 | 0.84 | ADRB2 (0.64) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL12122747 | 0.84 | ADRB1 (0.68) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL6277059 | 0.83 | ADRB1 (0.67) | ADRB1ADRB2CYP2D6NR3C1ADRA1A | |
| SCHEMBL13640085 | 0.83 | KMT2A (0.61) | ADRB1ADRB2CYP2D6NR3C1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190867-A | Process for the preparation of R-2,2-R1,R2 -1,3-dioxolane-4-methanol | SHELL INTERNATIONAL PETROLEUM COMPANY, LTD. (GB) | 1993-03-02 | — | — | US | disclosed |
| EP-0487237-A1 | New optically active metoprolol tartrate salts, and method of preparing them, and method of preparing optically active metoprolol from the tartrate salts | Nitto Denko Co. Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4871775-A | TREATING VISION DEFECTS | BEIERSDORF AG (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0244912-A1 | A process for the preparation of R and S-2,2-R1,R2-1,3-dioxolane-4-methanol | GIST-BROCADES N.V. (NL) | 1987-11-11 | — | — | EP | disclosed |
| EP-0082461-B1 | SUBSTITUTED PHENOXYALKANOL AMINES AND PHENOXYALKANOL-CYCLOALKYL AMINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES | Beiersdorf Aktiengesellschaft (DE) | 1987-03-04 | — | — | EP | disclosed |
| EP-0082461-A2 | Substituted phenoxyalkanol amines and phenoxyalkanol-cycloalkyl amines, process for their preparation, pharmaceutical compositions containing them and intermediates | Beiersdorf Aktiengesellschaft (DE) | 1983-06-29 | — | — | EP | disclosed |