Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 4/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376318 | 0.83 | HPGD (0.38) | HPGDNOS2MEN1KMT2AL3MBTL1 | |
| SCHEMBL13082114 | 0.81 | KDM4E (0.38) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25614134 | 0.81 | NOS3 (0.40) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17859388 | 0.81 | HSD17B10 (0.38) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16884625 | 0.79 | LRRK2 (0.37) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6637905 | 0.79 | USP7 (0.39) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13082566 | 0.79 | AR (0.37) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7213760 | 0.78 | NOS2 (0.40) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25983686 | 0.75 | AR (0.35) | HPGDCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7215618 | 0.75 | HPGD (0.42) | HPGDNOS2PDE3BPDE3AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |