Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27939135 | 0.85 | TSHR (0.54) | TSHRLMNACNR1ALDH1A1HSD17B10 | |
| SCHEMBL6379635 | 0.83 | NR4A2 (0.69) | TSHRLMNACNR1ALDH1A1NR4A2 | |
| SCHEMBL13936213 | 0.83 | NR4A2 (0.69) | TSHRLMNAALDH1A1NR4A2KDM4E | |
| SCHEMBL2090257 | 0.82 | NR4A2 (0.76) | TSHRLMNACNR1ALDH1A1NR4A2 | |
| SCHEMBL2457012 | 0.82 | KMT2A (0.64) | TSHRLMNACNR1ALDH1A1NR4A2 | |
| SCHEMBL15363131 | 0.80 | ALDH1A1 (0.70) | LMNACNR1ALDH1A1NR4A2KDM4E | |
| SCHEMBL28806864 | 0.79 | NR4A2 (0.72) | TSHRLMNACNR1ALDH1A1NR4A2 | |
| SCHEMBL8694448 | 0.78 | KMT2A (0.68) | TSHRLMNACNR1ALDH1A1NR4A2 | |
| Hydrochloric Acid SCHEMBL7218094 | 0.78 | CNR1 (0.48) | TSHRLMNACNR1ALDH1A1HSD17B10 | |
| SCHEMBL15175852 | 0.77 | KDM4E (0.52) | TSHRLMNACNR1ALDH1A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596726-B1 | Method of inhibiting epidermal growth factor by treating, with an effective inhibiting amount, a mammal, in need thereof inhibit the epidermal growth factor receptor and related receptors and, in particular, their tyrosine kinase enzyme | WARNER LAMBERT COMPANY | 2003-07-22 | — | — | US | disclosed |
| US-5679683-A | USEFUL FOR TREATING CANCER, ARTHRITIS, PSORIASIS, VASCULAR RESTENOSIS AND ANGIOGENESIS | WARNER-LAMBERT COMPANY (US) | 1997-10-21 | — | — | US | disclosed |