Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560375 | 0.89 | L3MBTL1 (0.67) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL2117439 | 0.87 | KMT2A (0.55) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL6379635 | 0.83 | NR4A2 (0.69) | KMT2AMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL2114760 | 0.83 | L3MBTL1 (0.54) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL7215714 | 0.82 | TSHR (0.54) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL27939135 | 0.82 | TSHR (0.54) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL2090257 | 0.82 | NR4A2 (0.76) | ALDH1A1LMNASMN1; SMN2TSHRCNR1 | |
| SCHEMBL6283431 | 0.81 | L3MBTL1 (0.53) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL16795100 | 0.81 | ALDH1A1 (0.51) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL8021031 | 0.81 | L3MBTL1 (0.63) | KMT2AMEN1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140128571-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2014-05-08 | — | — | US | disclosed |
| US-20130165630-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2013-06-27 | — | — | US | disclosed |
| US-20120302780-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-11-29 | — | — | US | disclosed |
| US-20110237776-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302780-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | CBS, ARSA, SOD1 | KMT2A 2298/4885MEN1 4362/4885MAPT 2812/4885 |
| US-20140128571-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | SOD1, CBS, ABCB7 | KMT2A 2179/4885MEN1 4105/4885MAPT 2316/4885 |
| US-20110237776-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | SOD1, CBS, ABCB7 | KMT2A 2179/4885MEN1 4105/4885MAPT 2316/4885 |
| US-20130165630-A1 | AROMATIC COMPOUNDS WITH SULFUR CONTAINING LIGANDS | SOD1, CBS, ABCB7 | KMT2A 2179/4885MEN1 4105/4885MAPT 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.