Ethylene Glycol

Ethylene Glycol

SCHEMBL7215786

O=C(O)CC(c1ccncc1)c1ccncc1.OCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 1/20 0.42
MMP13 P45452 1/20 0.42
FFAR1 O14842 2/20 0.41
LMNA P02545 1/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
NAPRT Q6XQN6 1/20 0.40
CTSA P10619 3/20 0.39
EPHX2 P34913 1/20 0.39
HMOX2 P30519 1/20 0.38
BCHE P06276 1/20 0.38
PLOD2 O00469 1/20 0.37
PLOD3 O60568 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170301 0.88 SLC6A2 (0.55) MMP12MMP13FFAR1LMNASLC6A2
Hydrochloric Acid SCHEMBL128794 0.86 SLC6A2 (0.53) MMP12MMP13FFAR1LMNASLC6A2
SCHEMBL5705693 0.83 FFAR1 (0.50) FFAR1LMNACTSAEPHX2HPGD
SCHEMBL7215779 0.78 CYP19A1 (0.43) LMNASLC6A2SLC6A4SLC6A3NAPRT
SCHEMBL3526103 0.78 MMP12 (0.47) MMP12MMP13SLC6A2SLC6A4SLC6A3
SCHEMBL4449939 0.78 MMP12 (0.47) MMP12MMP13SLC6A2SLC6A4SLC6A3
SCHEMBL1677568 0.76 FFAR1 (0.54) MMP12MMP13FFAR1SLC6A2SLC6A4
SCHEMBL2999878 0.76 GRM8 (0.43) MMP12MMP13SLC6A2SLC6A4SLC6A3
SCHEMBL5720968 0.76 GRM8 (0.43) MMP12MMP13SLC6A2SLC6A4SLC6A3
SCHEMBL3908031 0.76 L3MBTL1 (0.56) MMP12MMP13LMNASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6617474-B2 Reacting olefinically unsaturated compound with carbon monoxide and hydrogen in presence of polar phase comprising: a non-aqueous ionic liquid comprising quaternary ammonium and/or a quaternary phosphonium compound and catalyst; adding solvent INSTITUT FRANCAIS DU PETROLE (FR) 2003-09-09 US disclosed
US-20020099243-A1 Process for the hydroformylation of olefinically unsaturated compounds in a non-aqueous ionic solvent INSTITUT FRANCAIS DU PETROLE (FR) 2002-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020099243-A1 Process for the hydroformylation of olefinically unsaturated compounds in a non-aqueous ionic solvent NUDT1, PHOSPHO1, SRSF6 MMP12 4216/4885MMP13 4364/4885FFAR1 2075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.