Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7215801

NC(=O)[C@@H]1CCN(Cc2cc3ncccc3[nH]2)C1=O.O=C(O)C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 1/20 0.40
PRMT5 O14744 3/20 0.39
WDR77 Q9BQA1 3/20 0.39
F10 P00742 5/20 0.39
HRH4 Q9H3N8 1/20 0.36
DAO P14920 1/20 0.36
DPP4 P27487 1/20 0.35
DPP7 Q9UHL4 1/20 0.35
SYK P43405 1/20 0.34
PAX8 Q06710 1/20 0.34
MET P08581 1/20 0.34
PRSS1 P07477 2/20 0.33
F2 P00734 1/20 0.33
ATAD2 Q6PL18 1/20 0.33
NR3C1 P04150 1/20 0.33
PDE10A Q9Y233 1/20 0.33
CNR2 P34972 1/20 0.33
PLAT P00750 1/20 0.33
PROC P04070 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7215805 0.88 RBP4 (0.41) RBP4PRMT5WDR77F10HRH4
Trifluoroacetic Acid SCHEMBL7219215 0.81 F10 (0.46) RBP4PRMT5WDR77F10HRH4
Trifluoroacetic Acid SCHEMBL7214368 0.81 F10 (0.46) RBP4PRMT5WDR77F10HRH4
SCHEMBL6248107 0.79 F10 (0.44) RBP4PRMT5WDR77F10HRH4
Trifluoroacetic Acid SCHEMBL7219143 0.77 DRD4 (0.35) F10MET
SCHEMBL7214183 0.77 F10 (0.37) PRMT5WDR77F10HRH4PRSS1
Trifluoroacetic Acid SCHEMBL7220303 0.76 ATM (0.37)
Trifluoroacetic Acid SCHEMBL7915310 0.74 MET (0.40) F10METPRSS1F2
Trifluoroacetic Acid SCHEMBL7923391 0.74 MET (0.40) F10METPRSS1F2
Trifluoroacetic Acid SCHEMBL7220554 0.74 MET (0.38) F10DPP4DPP7METPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944386-B1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMA INC (US) 2002-09-18 EP claimed
EP-0944386-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2001-04-11 EP claimed
EP-0944386-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-09-29 EP claimed
WO-1998025611-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-06-18 WO claimed
US-6602864-B1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-08-05 US disclosed
EP-0944386-B1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMA INC (US) 2002-09-18 EP disclosed
EP-1086099-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2002-01-02 EP disclosed
US-6281227-B1 INHIBITORS OF THE ACTIVITY OF FACTOR XA. AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-08-28 US disclosed
EP-0944386-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2001-04-11 EP disclosed
EP-1086099-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS Aventis Pharmaceuticals Products Inc. (US) 2001-03-28 EP disclosed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO disclosed
EP-0944386-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-09-29 EP disclosed
WO-1998025611-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-06-18 WO disclosed