Trifluoroacetic Acid

SCHEMBL7923391

NC(=O)[C@@H]1CCN(Cc2ccc3c(N)ccnc3c2)C1=O.O=C(O)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	MET	P08581	1/20	0.40

▸	GRM2	Q14416	11/20	0.35

▸	F10	P00742	7/20	0.35

▸	NR1I2	O75469	1/20	0.35

▸	KCNH2	Q12809	1/20	0.35

▸	F2	P00734	3/20	0.34

▸	PRSS1	P07477	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Trifluoroacetic Acid SCHEMBL7915310	1.00	MET (0.40)	METGRM2F10NR1I2KCNH2
SCHEMBL7921780	0.93	MET (0.40)	METGRM2F10NR1I2KCNH2
SCHEMBL6224791	0.93	MET (0.40)	METGRM2F10NR1I2KCNH2
Trifluoroacetic Acid SCHEMBL7220554	0.93	MET (0.38)	METGRM2F10F2PRSS1
Trifluoroacetic Acid SCHEMBL7923392	0.89	F10 (0.36)	METGRM2F10NR1I2KCNH2
Trifluoroacetic Acid SCHEMBL6220784	0.87	F10 (0.46)	METF10
Trifluoroacetic Acid SCHEMBL7409145	0.87	F10 (0.46)	METF10
SCHEMBL7921803	0.85	SMYD3 (0.40)	METF10F2PRSS1
Trifluoroacetic Acid SCHEMBL7214503	0.85	F10 (0.47)	F10KCNH2F2
Trifluoroacetic Acid SCHEMBL7213654	0.83	F10 (0.47)	METF10F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6281227-B1	INHIBITORS OF THE ACTIVITY OF FACTOR XA.	AVENTIS PHARMA DEUTSCHLAND GMBH (DE)	2001-08-28	—	—	US	claimed
US-6281227-B1	INHIBITORS OF THE ACTIVITY OF FACTOR XA.	AVENTIS PHARMA DEUTSCHLAND GMBH (DE)	2001-08-28	—	—	US	disclosed