Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.66 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11831331 | 0.98 | HTR2C (0.67) | HTR2CDRD2ADRA1AHTR1AADRA1D | |
| SCHEMBL1515134 | 0.91 | HTR2C (0.77) | HTR2CDRD2ADRA1AHTR1AADRA1D | |
| SCHEMBL30997824 | 0.91 | HTR2C (0.77) | HTR2CDRD2ADRA1AHTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL7050981 | 0.89 | HTR2C (0.59) | HTR2CDRD2ADRA1AHTR1AADRA1D | |
| Methyl Alcohol SCHEMBL8097139 | 0.87 | HTR2C (0.72) | HTR2CDRD2ADRA1AHTR1AADRA1D | |
| Ethylamine SCHEMBL8089244 | 0.86 | HTR2C (0.66) | HTR2CDRD2ADRA1AHTR1AADRA1D | |
| SCHEMBL28695004 | 0.84 | HTR2C (0.68) | HTR2CDRD2ADRA1AHTR1AADRA1D | |
| SCHEMBL7844832 | 0.84 | HTR2C (0.72) | HTR2CDRD2ADRA1AHTR1AADRA1D | |
| SCHEMBL1515075 | 0.84 | HTR2C (0.72) | HTR2CDRD2ADRA1AHTR1AADRA1D | |
| SCHEMBL28695001 | 0.83 | HTR2C (0.66) | HTR2CDRD2ADRA1AHTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315750-A2 | CYCLIC PEPTIDES HAVING MELANOCORTIN-4 RECEPTOR AGONIST ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002018437-A2 | CYCLIC PEPTIDES HAVING MELANOCORTIN-4 RECEPTOR AGONIST ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-07 | — | — | WO | disclosed |