Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 17/20 | 0.47 |
| ▸ | CALML3 | P27482 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607503 | 0.84 | CALML3 (0.47) | MAOACALML3 | |
| SCHEMBL7077703 | 0.84 | MAOA (0.46) | MAOACALML3MAOB | |
| SCHEMBL6609246 | 0.84 | MAOA (0.46) | MAOACALML3 | |
| SCHEMBL6607500 | 0.83 | CALML3 (0.54) | MAOACALML3MAOB | |
| SCHEMBL6609507 | 0.83 | MAOA (0.47) | MAOACALML3 | |
| SCHEMBL6607943 | 0.82 | MAOA (0.49) | MAOACALML3MAOB | |
| SCHEMBL6607708 | 0.82 | MAOA (0.46) | MAOACALML3MAOB | |
| SCHEMBL7082522 | 0.82 | MAOA (0.45) | MAOACALML3MAOB | |
| SCHEMBL6606974 | 0.82 | MAOA (0.46) | MAOACALML3MAOB | |
| SCHEMBL5234653 | 0.81 | MAOA (0.47) | MAOACALML3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617339-B1 | 5-Isoxazolyloxymethyl-3-((dihydroxypropanoyl)-4-tetrahydropyri dyl-3,5- difluorophenyl)oxazolidinone, or the phosphated derivative or its disodium salt; antibiotic with useful activity against Grampositive pathogens | SYNGENTA LIMITED (GB) | 2003-09-09 | — | — | US | disclosed |