Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216204 | 1.00 | ALDH1A1 (0.69) | ALDH1A1HSD17B10MEN1KMT2AOPRM1 | |
| SCHEMBL6490794 | 0.95 | ALDH1A1 (0.74) | ALDH1A1HSD17B10MEN1KMT2AOPRM1 | |
| SCHEMBL6490798 | 0.95 | ALDH1A1 (0.74) | ALDH1A1HSD17B10MEN1KMT2AOPRM1 | |
| SCHEMBL1513400 | 0.81 | DRD2 (0.62) | ALDH1A1HSD17B10OPRM1OPRL1DRD2 | |
| SCHEMBL7211690 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MEN1KMT2AOPRM1 | |
| SCHEMBL7211693 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MEN1KMT2AOPRM1 | |
| SCHEMBL7222128 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MEN1KMT2AOPRM1 | |
| SCHEMBL2590886 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MEN1KMT2AOPRM1 | |
| SCHEMBL4811473 | 0.74 | OPRM1 (0.54) | ALDH1A1HSD17B10OPRM1OPRL1DRD2 | |
| SCHEMBL9911015 | 0.74 | DRD2 (0.76) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984966-B1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH AS (DK) | 2003-01-29 | — | — | EP | disclosed |
| US-6392045-B1 | 9-azobicyclo[3.3.1] non-2-ene derivatives as cholinergic ligands at nicotinic ACH receptors | NEUROSEARCH A/S (DK) | 2002-05-21 | — | — | US | disclosed |
| EP-0984966-A1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH A/S (DK) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054182-A1 | 9-AZABICYCLO(3.3.1)NON-2-ENE AND NONANE DERIVATIVES AS CHOLINERGIC LIGANDS AT NICOTINIC ACh RECEPTORS | NEUROSEARCH A/S (DK) | 1998-12-03 | — | — | WO | disclosed |