Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27802846 | 0.85 | ALDH1A1 (0.39) | ALDH1A1CHRNA4SLC6A2HTR2ASLC6A4 | |
| SCHEMBL27802870 | 0.81 | TNNC1 (0.41) | ALDH1A1HTR2ATHRATHRBCA1 | |
| SCHEMBL27781275 | 0.80 | ALDH1A1 (0.38) | ALDH1A1CHRNA4SLC6A2TDP1HTR2A | |
| SCHEMBL27520515 | 0.80 | SLC6A2 (0.55) | ALDH1A1CHRNA4SLC6A2TDP1HTR2A | |
| SCHEMBL27802903 | 0.80 | TNNC1 (0.43) | ALDH1A1HTR2ATHRATHRBCA1 | |
| SCHEMBL27802899 | 0.80 | TNNC1 (0.43) | ALDH1A1HTR2ATHRATHRBCA1 | |
| SCHEMBL27781297 | 0.80 | TNNC1 (0.43) | ALDH1A1HTR2ATHRATHRBCA1 | |
| SCHEMBL6289217 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CHRNA4SLC6A2TDP1HTR2A | |
| SCHEMBL6751395 | 0.78 | KDM4E (0.42) | ALDH1A1CHRNA4TDP1CHRNB2CHRNB4 | |
| SCHEMBL16301950 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CHRNA4CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030125467-A1 | A crosslinked rubber particles containing conjugated diene monomer, aromatic vinyl monomer and monomer with at least two polymerizable unsaturated groups dispersed in a conjugated diene/aromatic vinyl copolymer; resist to rolling, skid, wear | JSR CORPORATION (JP) | 2003-07-03 | — | — | US | claimed |
| EP-0245505-B2 | TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER | ASAHI CHEMICAL IND (JP) | 1996-08-14 | — | — | EP | claimed |
| CN-103274937-B | Soot dispersion agent and the lubricating oil composition containing this dispersion agent | ENFENORM INTERNATIONAL CO. (GB) | 2016-02-03 | — | — | CN | disclosed |
| EP-0430528-A1 | Lube oil additive package containing viscosity index improver | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-06-05 | — | — | EP | disclosed |