Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289217 | 0.81 | ALDH1A1 (0.44) | ALDH1A1THRATHRBESR1CHRNB2 | |
| SCHEMBL1611980 | 0.78 | THRA (0.53) | ALDH1A1THRATHRBESR1CHRNB2 | |
| SCHEMBL7216235 | 0.76 | ALDH1A1 (0.42) | ALDH1A1THRATHRBESR1CHRNB2 | |
| SCHEMBL10597489 | 0.75 | ALDH1A1 (0.46) | ALDH1A1THRATHRBESR1CHRNB2 | |
| SCHEMBL21330385 | 0.75 | ALDH1A1 (0.46) | ALDH1A1THRATHRBESR1CHRNB2 | |
| SCHEMBL27520515 | 0.75 | SLC6A2 (0.55) | ALDH1A1THRATHRBESR1CHRNB2 | |
| SCHEMBL24692108 | 0.74 | ALDH1A1 (0.41) | ALDH1A1THRATHRBESR1CHRNB2 | |
| SCHEMBL21323058 | 0.74 | SLC6A2 (0.52) | ALDH1A1 | |
| SCHEMBL5199704 | 0.73 | ALDH1A1 (0.44) | ALDH1A1THRATHRBESR1CHRNB2 | |
| SCHEMBL20341248 | 0.73 | ALDH1A1 (0.44) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771548-B1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NAT RECH SCIENT (FR) | 2012-06-27 | — | — | EP | disclosed |