Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.82 |
| ▸ | CHRNA7 | P36544 | 15/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215274 | 0.90 | PTGS2 (1.00) | PTGS2CHRNA7 | |
| SCHEMBL7216763 | 0.81 | CHRNA7 (0.62) | PTGS2CHRNA7 | |
| SCHEMBL7216536 | 0.80 | PTGS2 (0.81) | PTGS2CHRNA7 | |
| SCHEMBL7211892 | 0.80 | PTGS2 (0.81) | PTGS2CHRNA7CYP2D6 | |
| SCHEMBL7216230 | 0.79 | PTGS2 (0.79) | PTGS2CHRNA7CYP2D6 | |
| SCHEMBL7210628 | 0.77 | CHRNA7 (0.62) | PTGS2CHRNA7 | |
| SCHEMBL7210344 | 0.77 | PTGS2 (1.00) | PTGS2CHRNA7 | |
| SCHEMBL7216347 | 0.76 | CHRNA7 (0.70) | PTGS2CHRNA7 | |
| SCHEMBL3025893 | 0.76 | CHRNA7 (0.83) | CHRNA7CYP2D6 | |
| SCHEMBL3015089 | 0.76 | CHRNA7 (0.86) | PTGS2CHRNA7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | disclosed |