Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216281 | 0.90 | PTGS2 (0.82) | PTGS2CHRNA7 | |
| SCHEMBL7210344 | 0.87 | PTGS2 (1.00) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL5311097 | 0.84 | PTGS2 (0.77) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL1382367 | 0.82 | PTGS2 (0.78) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL7212003 | 0.82 | PTGS2 (1.00) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL7212067 | 0.80 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL5965074 | 0.80 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL7210593 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7215275 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7212040 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | claimed |
| EP-1369415-A1 | Substituted pyrrolyl compounds for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2003-12-10 | — | — | EP | disclosed |