Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CPA3 | P15088 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532188 | 1.00 | CA12 (0.51) | CA12CA9NPC1RAB9AADRA2B | |
| SCHEMBL7425740 | 1.00 | CA12 (0.51) | CA12CA9NPC1RAB9AADRA2B | |
| Hydrochloric Acid SCHEMBL27713536 | 0.98 | CA12 (0.50) | CA12CA9NPC1RAB9AADRA2B | |
| SCHEMBL27505416 | 0.87 | ALDH1A1 (0.46) | CA12CA9NPC1RAB9AADRA2B | |
| SCHEMBL8797866 | 0.84 | NPC1 (0.49) | CA12CA9NPC1RAB9AADRA2B | |
| SCHEMBL8797872 | 0.84 | NPC1 (0.49) | CA12CA9NPC1RAB9AADRA2B | |
| SCHEMBL7140937 | 0.84 | NPC1 (0.49) | CA12CA9NPC1RAB9AADRA2B | |
| SCHEMBL7469312 | 0.84 | NPC1 (0.49) | CA12CA9NPC1RAB9AADRA2B | |
| SCHEMBL1416482 | 0.84 | NR4A2 (0.58) | CA12CA9NPC1RAB9AADRA2B | |
| SCHEMBL10723226 | 0.84 | NR4A2 (0.58) | CA12CA9NPC1RAB9AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355940-A2 | UROTENSIN-II AGONISTS AND ANTAGONISTS | The Administrators of The Tulane Educational Fund (US) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002032932-A2 | UROTENSIN-II AGONISTS AND ANTAGONISTS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2002-04-25 | — | — | WO | disclosed |
| WO-1991009051-A1 | SUBSTITUTED CYCLIC PENICILLANIC ACID TETRAPEPTIDES | G.D. SEARLE & CO. (US) | 1991-06-27 | — | — | WO | disclosed |