Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.39 |
| ▸ | ITGAV | P06756 | 19/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212704 | 0.94 | ITGB3 (0.42) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211505 | 0.88 | ITGB3 (0.42) | ITGB3ITGAVITGA2B | |
| SCHEMBL7211648 | 0.84 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7217610 | 0.82 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211342 | 0.82 | ITGB3 (0.43) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7211540 | 0.82 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7217673 | 0.82 | ALOX15 (0.31) | ITGB3ITGAV | |
| SCHEMBL7217767 | 0.81 | ITGB3 (0.44) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7216491 | 0.80 | ITGB3 (0.40) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL7217515 | 0.80 | ITGB3 (0.47) | ITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620820-B2 | Imidazole dione or one, thione derivatives as antitumor and antiinflammatory agents, also treats cardiovascular disease, nephropathies and retinopathies | HOECHST AKTIENGESELLSCHAFT (DE) | 2003-09-16 | — | — | US | disclosed |
| US-6218415-B1 | THERAPY OF BONE REABSORPTION BY OSTEOCLASTS, TUMOR GROWTH AND TUMOR METASTASIS, INFLAMMATION, CARDIOVASCULAR DISEASE, NEPHROPATHIES AND RETINOPATHIES | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-04-17 | — | — | US | disclosed |