Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 5/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215961 | 0.94 | HRH3 (0.39) | HRH3RXRBRXRALMNAL3MBTL1 | |
| SCHEMBL7222916 | 0.93 | RXRB (0.37) | HRH3RXRBRXRALMNANPC1 | |
| SCHEMBL7223004 | 0.92 | SMN1; SMN2 (0.43) | RXRBRXRALMNAL3MBTL1CYP2C19 | |
| SCHEMBL7221445 | 0.91 | FFAR1 (0.39) | HRH3RXRBRXRANPC1RAB9A | |
| SCHEMBL7223497 | 0.91 | LMNA (0.44) | LMNAL3MBTL1CYP2C19NPC1RAB9A | |
| SCHEMBL7218340 | 0.89 | LTA4H (0.40) | LMNAL3MBTL1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL7221889 | 0.87 | NR4A2 (0.48) | HRH3RXRBRXRALMNACYP2C19 | |
| SCHEMBL7218316 | 0.86 | NR4A2 (0.47) | HRH3RXRBRXRANPC1RAB9A | |
| SCHEMBL7252964 | 0.86 | RARB (0.40) | LMNAL3MBTL1CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL7215727 | 0.86 | KMT2A (0.44) | LMNAL3MBTL1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |