Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | ACACA | Q13085 | 4/20 | 0.35 |
| ▸ | FABP1 | P07148 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7222487 | 0.94 | RARB (0.38) | LTA4HTSHRLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL7215727 | 0.93 | KMT2A (0.44) | LMNAL3MBTL1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7216635 | 0.89 | LTA4H (0.39) | LTA4HTSHRMAPK1SMN1; SMN2ACACB | |
| SCHEMBL7252964 | 0.89 | RARB (0.40) | TSHRLMNAL3MBTL1KMT2ACYP2C19 | |
| SCHEMBL7216554 | 0.89 | HRH3 (0.43) | TSHRLMNAL3MBTL1KMT2ACYP2C19 | |
| SCHEMBL7223497 | 0.88 | LMNA (0.44) | TSHRLMNAL3MBTL1KMT2ACYP2C19 | |
| SCHEMBL7215993 | 0.87 | KMT2A (0.39) | LMNAL3MBTL1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7222347 | 0.87 | ACACB (0.35) | KMT2AACACBACACA | |
| SCHEMBL7972262 | 0.85 | RARB (0.45) | TSHRKMT2ASMN1; SMN2TP53 | |
| SCHEMBL7216131 | 0.84 | MAPT (0.36) | LTA4HLMNAMAPK1SMN1; SMN2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |