Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | HTR5A | P47898 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841248 | 0.80 | HTR5A (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29789738 | 0.80 | HTR5A (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29976025 | 0.73 | GAA (0.43) | CYP3A4CYP2C19 | |
| SCHEMBL2125224 | 0.73 | GAA (0.43) | CYP3A4CYP2C19 | |
| SCHEMBL29976397 | 0.69 | ATM (0.46) | CA4OPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL19216987 | 0.69 | KMT2A (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28547293 | 0.69 | ATM (0.46) | CA4OPRM1OPRL1SMN1; SMN2 | |
| SCHEMBL29976016 | 0.69 | OPRD1 (0.40) | CA1CA2CA7CA9OPRM1 | |
| SCHEMBL28555387 | 0.69 | OPRD1 (0.40) | CA1CA2CA7CA9OPRM1 | |
| SCHEMBL19457182 | 0.64 | ADRB2 (0.54) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617336-B1 | Treatment of urinary incontinence, venous insufficiency, migraine or gastrointestinal disorders | SANOFI-SYNTHELABO (FR) | 2003-09-09 | — | — | US | disclosed |