SCHEMBL7216895

SCHEMBL7216895

Fc1ncc(Sc2ccccc2)cc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GRM5 P41594 1/20 0.36
HPGD P15428 2/20 0.36
HTT P42858 1/20 0.36
KDM4E B2RXH2 3/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2C9 P11712 3/20 0.35
CYP2C19 P33261 2/20 0.35
L3MBTL1 Q9Y468 3/20 0.34
PDE7A Q13946 1/20 0.34
LMNA P02545 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HTR6 P50406 1/20 0.33
ABL1 P00519 1/20 0.33
CHRNA7 P36544 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7215091 0.86 HAO1 (0.43) ALDH1A1NPSR1MEN1KMT2AGRM5
SCHEMBL7214404 0.85 KDM4E (0.44) ALDH1A1MEN1KMT2AGRM5HPGD
SCHEMBL7216726 0.83 HAO1 (0.40) ALDH1A1NPSR1MEN1KMT2AGRM5
SCHEMBL7215177 0.82 MAPK13 (0.41) MEN1KMT2AGRM5HPGDKDM4E
SCHEMBL28750626 0.79 LOXL2 (0.36) MEN1KMT2AMAPT
SCHEMBL7220812 0.79 GCK (0.40) ALDH1A1MEN1KMT2AGRM5HPGD
SCHEMBL21773120 0.77 HSD17B10 (0.42) ALDH1A1NPSR1MEN1KMT2AHTT
SCHEMBL21783355 0.75 HAO1 (0.30)
SCHEMBL4199869 0.71 TP53 (0.43) ALDH1A1GRM5HPGDHTTKDM4E
SCHEMBL30094521 0.69 MAOA (0.41) ALDH1A1HPGDHTTKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6559170-B1 Compounds are useful as fungicides in plants DOW AGROSCIENCE LLC 2003-05-06 US disclosed
EP-1237870-A1 PYRIDINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO PRODUCE AND USE THE SAME Dow AgroSciences LLC (US) 2002-09-11 EP disclosed
WO-2001044196-A1 PYRIDINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO PRODUCE AND USE THE SAME DOW AGROSCIENCES, LLC (US) 2001-06-21 WO disclosed