Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220812 | 0.79 | GCK (0.40) | TP53MAPTGCKHPGDHTT | |
| SCHEMBL13486492 | 0.72 | KDM4E (0.40) | TP53MAPTGCKHPGDHTT | |
| SCHEMBL10648752 | 0.72 | MAPT (0.46) | TP53MAPTHPGDALDH1A1GRM5 | |
| SCHEMBL2849379 | 0.72 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4E | |
| SCHEMBL7216895 | 0.71 | ALDH1A1 (0.38) | TP53MAPTGCKHPGDHTT | |
| SCHEMBL11887379 | 0.70 | ALDH1A1 (0.42) | TP53MAPTGCKHPGDALDH1A1 | |
| SCHEMBL9901278 | 0.70 | MAPT (0.43) | TP53MAPTHPGDHTTALDH1A1 | |
| SCHEMBL30094521 | 0.69 | MAOA (0.41) | TP53MAPTHPGDHTTALDH1A1 | |
| SCHEMBL10007323 | 0.69 | ALDH1A1 (0.47) | TP53MAPTHPGDALDH1A1CYP1A2 | |
| SCHEMBL30618060 | 0.68 | HPGD (0.56) | MAPTHPGDHTTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101326161-B | Novel compounds | ASTRAZENECA AB | 2013-04-17 | — | — | CN | disclosed |
| US-20090192163-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | US | disclosed |
| CN-101326161-A | Novel compounds | ASTRAZENECA AB (SE) | 2008-12-17 | — | — | CN | disclosed |
| EP-1937632-A1 | NOVEL COMPOUNDS | Astra Zeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007039736-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192163-A1 | Novel Compounds | PAH, PC, DDC | TP53 3301/4885MAPT 1713/4885GCK 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.