Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.74 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.66 |
| ▸ | CA2 | P00918 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31300108 | 0.99 | CYP3A4 (0.75) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 | |
| SCHEMBL14871096 | 0.96 | CYP3A4 (0.78) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 | |
| SCHEMBL197081 | 0.96 | CYP3A4 (0.78) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 | |
| SCHEMBL5440315 | 0.93 | CYP3A4 (0.73) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 | |
| SCHEMBL5438281 | 0.93 | CYP3A4 (0.80) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 | |
| SCHEMBL6346047 | 0.92 | CYP3A4 (0.74) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 | |
| SCHEMBL13360010 | 0.91 | CYP3A4 (0.72) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 | |
| SCHEMBL7199293 | 0.90 | CYP3A4 (0.77) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 | |
| SCHEMBL7196373 | 0.90 | CYP3A4 (0.77) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 | |
| SCHEMBL2973416 | 0.90 | CYP3A4 (0.79) | CYP3A4KMT2AMEN1SLCO1B3SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187749-A1 | NOVEL REAGENT AND METHOD EMPLOYING SAME | BECKMAN INSTRUMENTS, INC. (US) | 1986-07-23 | — | — | EP | claimed |
| WO-1986000933-A1 | NOVEL REAGENT AND METHOD EMPLOYING SAME | BECKMAN INSTRUMENTS, INC. (US) | 1986-02-13 | — | — | WO | claimed |
| EP-2438166-B1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | CANON KK (JP) | 2015-11-11 | — | — | EP | disclosed |
| US-9169480-B2 | Method for preparing protein, DNA, and RNA from cell | CANON KABUSHIKI KAISHA (JP) | 2015-10-27 | — | — | US | disclosed |
| EP-2438166-A1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | Canon Kabushiki Kaisha (JP) | 2012-04-11 | — | — | EP | disclosed |
| US-20120053329-A1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | CANON KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| WO-2010140598-A1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | CANON KABUSHIKI KAISHA (JP) | 2010-12-09 | — | — | WO | disclosed |
| US-20100055675-A1 | METHOD FOR DETECTING MEASLES VIRUS, MEMBRANE ASSAY TEST DEVICE, AND MEMBRANE ASSAY TEST KIT | SYSMEX CORPORATION (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-0187749-A1 | NOVEL REAGENT AND METHOD EMPLOYING SAME | BECKMAN INSTRUMENTS, INC. (US) | 1986-07-23 | — | — | EP | disclosed |
| WO-1986000933-A1 | NOVEL REAGENT AND METHOD EMPLOYING SAME | BECKMAN INSTRUMENTS, INC. (US) | 1986-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053329-A1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | DDX21, HNRNPR, NXF1 | CYP3A4 4705/4885KMT2A 2047/4885MEN1 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.