Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781732 | 1.00 | TDP1 (0.47) | TDP1CES2CES1APEX1PTGES | |
| SCHEMBL9781736 | 1.00 | TDP1 (0.47) | TDP1CES2CES1APEX1PTGES | |
| SCHEMBL578944 | 1.00 | TDP1 (0.47) | TDP1CES2CES1APEX1PTGES | |
| SCHEMBL15921378 | 0.94 | ALOX5 (0.49) | TDP1CES2CES1APEX1PTGES | |
| SCHEMBL2813286 | 0.87 | CES2 (0.41) | CES2CES1PTGESALOX5PPARG | |
| SCHEMBL2813288 | 0.87 | CES2 (0.41) | CES2CES1PTGESALOX5PPARG | |
| SCHEMBL6677695 | 0.83 | ALDH1A1 (0.36) | PTGESALOX5PPARGMEN1KMT2A | |
| SCHEMBL10816784 | 0.82 | POLB (0.42) | CES2CES1APEX1PTGESALOX5 | |
| SCHEMBL691461 | 0.80 | RECQL (0.39) | TDP1CES2CES1PTGESALOX5 | |
| SCHEMBL2807242 | 0.80 | RECQL (0.39) | TDP1CES2CES1PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177227-B1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORP (US) | 2003-10-01 | — | — | EP | claimed |