SCHEMBL721748

SCHEMBL721748

C[Zr](C)([SiH3])(Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.33
HTR6 P50406 1/20 0.33
SIGMAR1 Q99720 4/20 0.31
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8678682 0.83 SIGMAR1 (0.31) HTR2AHTR6SIGMAR1
SCHEMBL936685 0.81 SIGMAR1 (0.34) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL4428760 0.81 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL6441641 0.81 HTR6 (0.31) HTR2AHTR6
SCHEMBL6463698 0.79
SCHEMBL6448584 0.77 RET (0.31) HTR6RET
SCHEMBL5354275 0.77 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL7640273 0.76 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
Hydrochloric Acid SCHEMBL9069920 0.76 HTR2A (0.34) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL6443168 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557902-B2 Functionalizable synthetic hydrocarbon fluids and integrated method for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-15 US claimed
EP-2609125-A2 FUNCTIONALIZABLE SYNTHETIC HYDROCARBON FLUIDS AND INTEGRATED METHOD OF FOR PRODUCTION THEREOF ExxonMobil Chemical Patents Inc. (US) 2013-07-03 EP claimed
US-20120053309-A1 Functionalizable Synthetic Hydrocarbon Fluids and Integrated Method for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-03-01 US claimed
WO-2012027139-A2 FUNCTIONALIZABLE SYNTHETIC HYDROCARBON FLUIDS AND INTEGRATED METHOD OF FOR PRODUCTION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-03-01 WO claimed
US-9469704-B2 Utilization of linear alpha olefins in the production of metallocene catalyzed poly-alpha olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-10-18 US disclosed
US-9365663-B2 Production of shear-stable high viscosity PAO EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-06-14 US disclosed
US-8557902-B2 Functionalizable synthetic hydrocarbon fluids and integrated method for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-15 US disclosed
EP-2640757-A2 PROCESSES FOR MAKING MULTIMODAL MOLECULAR WEIGHT DISTRIBUTION POLYOLEFINS ExxonMobil Chemical Patents Inc. (US) 2013-09-25 EP disclosed
EP-2609125-A2 FUNCTIONALIZABLE SYNTHETIC HYDROCARBON FLUIDS AND INTEGRATED METHOD OF FOR PRODUCTION THEREOF ExxonMobil Chemical Patents Inc. (US) 2013-07-03 EP disclosed
US-20120149552-A1 Processes For Making Multimodal Molecular Weight Distribution Polyolefins EXXONMOBIL CHEMICAL PATENTS INC. 2012-06-14 US disclosed
WO-2012067777-A2 PROCESSES FOR MAKING MULTIMODAL MOLECULAR WEIGHT DISTRIBUTION POLYOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-05-24 WO disclosed
US-8148470-B1 Processes for making multimodal molecular weight distribution polyolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-03 US disclosed
US-20120053309-A1 Functionalizable Synthetic Hydrocarbon Fluids and Integrated Method for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2012-03-01 US disclosed
WO-2012027139-A2 FUNCTIONALIZABLE SYNTHETIC HYDROCARBON FLUIDS AND INTEGRATED METHOD OF FOR PRODUCTION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-03-01 WO disclosed
US-20090247442-A1 Production of Shear-Stable High Viscosity PAO EXXONMOBIL CHEMICAL PATENTS INC. 2009-10-01 US disclosed
US-20090221775-A1 Utilization Of Linear Alpha Olefins In The Production Of Metallocene Catalyzed Poly-Alpha Olefins EXXONMOBIL CHEMICAL PATENTS INC. 2009-09-03 US disclosed