Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5661565 | 0.89 | MAPT (0.49) | LTB4RLTB4R2PPARDMAPTL3MBTL1 | |
| SCHEMBL11856035 | 0.88 | LTB4R (0.50) | LTB4RLTB4R2PPARDMAPTL3MBTL1 | |
| SCHEMBL27485493 | 0.88 | PPARD (0.56) | LTB4RLTB4R2PPARDMAPTL3MBTL1 | |
| SCHEMBL73826 | 0.87 | CYP1A2 (0.52) | LTB4RLTB4R2PPARDMAPTL3MBTL1 | |
| SCHEMBL3032434 | 0.87 | LTB4R (0.52) | LTB4RLTB4R2PPARDMAPTCYP1A2 | |
| SCHEMBL73774 | 0.86 | LTB4R (0.48) | LTB4RLTB4R2PPARDMAPTL3MBTL1 | |
| SCHEMBL9027053 | 0.86 | ALDH1A1 (0.57) | MAPTL3MBTL1NPSR1ADRB2ADRB1 | |
| SCHEMBL10150312 | 0.86 | ALOX5 (0.51) | LTB4RLTB4R2PPARDMAPTL3MBTL1 | |
| SCHEMBL8723162 | 0.85 | LTB4R (0.54) | LTB4RLTB4R2PPARDMAPTADRB2 | |
| SCHEMBL11848031 | 0.85 | LTB4R (0.54) | LTB4RLTB4R2PPARDMAPTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627651-B1 | Exhibiting preventive and therapeutic effects against HIV infectious diseases wherein R1 is an optionally substituted five- or six-membered ring group; X1 is a free valency or the like; W is a divalent group and inhibitors of HIV (human | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| EP-1182195-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |