SCHEMBL7218065

SCHEMBL7218065

CCC(C)OC(=O)C(C)CC(C)C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
CYP19A1 P11511 1/20 0.33
FAAH O00519 1/20 0.33
RNPEP Q9H4A4 1/20 0.32
SLC7A5 Q01650 1/20 0.32
BIRC2 Q13490 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17878548 0.84 CYP19A1 (0.37) MAPTCYP19A1FAAHRNPEPSLC7A5
SCHEMBL4439936 0.84 MAPT (0.42) MAPTFAAH
SCHEMBL2978632 0.84 MAPT (0.42) MAPTFAAH
SCHEMBL2993049 0.84 MAPT (0.42) MAPTFAAH
SCHEMBL17878541 0.83 FAAH (0.41) CYP19A1FAAHRNPEPSLC7A5CYP3A4
SCHEMBL14552034 0.80 SLC1A3 (0.46) MAPT
SCHEMBL20749961 0.80 MAPT (0.36) MAPT
SCHEMBL17878544 0.80 PRKCA (0.41) RNPEP
SCHEMBL6741818 0.80 MAPT (0.40) MAPTFAAH
SCHEMBL6741820 0.80 MAPT (0.40) MAPTFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9771394-B2 Antimicrobial polymyxins for treatment of bacterial infections MICURX PHARMACEUTICALS, INC. (KY) 2017-09-26 US disclosed
US-20160185823-A1 ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS MICURX PHARMACEUTICALS, INC. 2016-06-30 US disclosed
US-6667285-B1 Branched-chain carboxylic acid monoalkyl ester with outstanding hydrolytic stability NEW JAPAN CHEMICAL CO., LTD. (JP) 2003-12-23 US disclosed
EP-1225213-A1 LUBRICATING OIL FOR REFRIGERATOR, HYDRAULIC FLUID COMPOSITION FOR REFRIGERATOR AND METHOD FOR LUBRICATION OF REFRIGERATOR NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160185823-A1 ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS VIP, AQP1, PEF1 MAPT 4274/4885CYP19A1 4560/4885FAAH 3284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.