SCHEMBL7218338

SCHEMBL7218338

C=CC(=O)Oc1ccccc1Cc1ccccc1O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.56
THRA P10827 1/20 0.56
HSPA5 P11021 1/20 0.50
AKR1B1 P15121 1/20 0.41
KEAP1 Q14145 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
IDO1 P14902 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
IDH1 O75874 1/20 0.35
TYMS P04818 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11240569 0.92 THRB (0.63) THRBTHRAMAPTKDM4EHPGD
SCHEMBL4342753 0.83 THRA (0.57) THRBTHRAHPGD
SCHEMBL218920 0.81 THRB (0.50) THRBTHRAESR1ESR2MAPT
SCHEMBL29497650 0.81 THRB (0.50) THRBTHRAESR1ESR2MAPT
SCHEMBL6219545 0.80 THRB (0.61) THRBTHRAMAPTKDM4EHPGD
SCHEMBL146450 0.80 THRB (0.70) THRBTHRAMAPTKDM4EHPGD
SCHEMBL10883970 0.80 THRB (0.54) THRBTHRAESR1ESR2TYMS
SCHEMBL7104109 0.80 THRB (0.51) THRBTHRAMAPTKDM4EHPGD
SCHEMBL2855272 0.79 THRB (0.60) THRBTHRAMAPTKDM4EHPGD
SCHEMBL311912 0.79 THRA (0.60) THRBTHRAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11111373-B2 Polymethacrylate composition and optical device made therefrom, and display apparatus CHI MEI CORPORATION (TW) 2021-09-07 US disclosed
US-20200181388-A1 POLYMETHACRYLATE COMPOSITION AND OPTICAL DEVICE MADE THEREFROM, AND DISPLAY APPARATUS CHI MEI CORPORATION (TW) 2020-06-11 US disclosed
EP-3502180-A1 POLYMETHACRYLATE COMPOSITION AND OPTICAL DEVICE MADE THEREFROM, AND DISPLAY APPARATUS Chi Mei Corporation (TW) 2019-06-26 EP disclosed
US-20190094725-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2019-03-28 US disclosed
EP-1367060-A1 GLUCOPYRANOSYLOXYBENZYLBENZENE DERIVATIVES AND MEDICINAL USE THEREOF Kissei Pharmaceutical Co., Ltd. (JP) 2003-12-03 EP disclosed