Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026935 | 0.87 | NPC1 (0.51) | THRBTHRAPTGER1PTGER4PTGER3 | |
| SCHEMBL4342753 | 0.87 | THRA (0.57) | THRBTHRADRD2TP53HPGD | |
| SCHEMBL11240569 | 0.87 | THRB (0.63) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL10717803 | 0.80 | L3MBTL1 (0.50) | PTGER1PTGER4PTGER3PTGER2HTT | |
| SCHEMBL29733421 | 0.80 | THRB (0.63) | THRBTHRAHTR1ADRD2PTGER1 | |
| SCHEMBL7218338 | 0.80 | THRB (0.56) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL21647816 | 0.77 | LRRK2 (0.47) | PTGER1FOLH1KDM4EALDH1A1LMNA | |
| SCHEMBL28924976 | 0.77 | KMT2A (0.52) | THRBTHRAKDM4EMEN1ALDH1A1 | |
| SCHEMBL4602976 | 0.77 | HTR1A (0.50) | HTR1APTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL27461371 | 0.76 | THRB (0.58) | THRBTHRAKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344780-A1 | GLUCOPYRANOSYLOXYBENZYL BENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-09-17 | — | — | EP | disclosed |