SCHEMBL7218349

SCHEMBL7218349

Cc1c(O)ccc2c1O2.Cc1ccc(P(c2ccc(O)cc2)c2ccc(O)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.41
ESR2 Q92731 8/20 0.39
ESR1 P03372 7/20 0.39
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
TYR P14679 1/20 0.32
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33480 0.79
SCHEMBL30301367 0.77 ESR2 (0.41) ESR2ESR1ALDH1A1TYR
SCHEMBL5966296 0.77 ACHE (0.68) ACHEESR2ESR1ALDH1A1HPGD
SCHEMBL5966312 0.77 ACHE (0.68) ACHEESR2ESR1ALDH1A1HPGD
Phenol SCHEMBL5049852 0.76 CA12 (0.42) ESR2ESR1ALDH1A1GLATYR
Formaldehyde SCHEMBL9717809 0.74 ESR2 (0.39) ESR2ESR1ALDH1A1TYR
Paraben SCHEMBL4654906 0.73 CA2 (0.52) ESR2ESR1ALDH1A1HPGDTYR
SCHEMBL3833957 0.66 ESR1 (0.78) ACHEESR2ESR1ALDH1A1HPGD
SCHEMBL34181 0.66 ACHE (0.57) ACHEESR2ESR1ALDH1A1HPGD
SCHEMBL15661400 0.66 ACHE (0.57) ACHEESR2ESR1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363922-A2 NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM Pabu Services, Inc. (US) 2003-11-26 EP disclosed
WO-2002066485-A2 NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM PABU SERVICES, INC. (US) 2002-08-29 WO disclosed