Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782920 | 1.00 | CTSK (0.45) | CTSKCTSSATMMAPTPPARA | |
| SCHEMBL8529886 | 1.00 | CTSK (0.45) | CTSKCTSSATMMAPTPPARA | |
| SCHEMBL9293004 | 1.00 | CTSK (0.45) | CTSKCTSSATMMAPTPPARA | |
| SCHEMBL10463737 | 0.91 | CTSK (0.43) | CTSKCTSSATMMAPT | |
| SCHEMBL8911849 | 0.91 | CTSK (0.43) | CTSKCTSSATMMAPTPPARA | |
| SCHEMBL8911855 | 0.88 | CTSK (0.41) | CTSKCTSSATMMAPTPPARA | |
| SCHEMBL7065105 | 0.87 | CTSK (0.41) | CTSKCTSSATMPPARAPPARG | |
| SCHEMBL9292986 | 0.83 | MAPT (0.45) | CTSKCTSSATMMAPTAKT1 | |
| SCHEMBL9293035 | 0.82 | ALDH1A1 (0.51) | — | |
| SCHEMBL8314307 | 0.82 | ALDH1A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596880-B1 | Esterification of baccatine derivative | AVENTIS PHARMA S.A. (FR) | 2003-07-22 | — | — | US | disclosed |