Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293123 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TSHR | |
| SCHEMBL3782920 | 0.83 | CTSK (0.45) | MAPTCTSKCTSSATMAKT1 | |
| SCHEMBL7218496 | 0.83 | CTSK (0.45) | MAPTCTSKCTSSATMAKT1 | |
| SCHEMBL9293004 | 0.83 | CTSK (0.45) | MAPTCTSKCTSSATMAKT1 | |
| SCHEMBL8529886 | 0.83 | CTSK (0.45) | MAPTCTSKCTSSATMAKT1 | |
| SCHEMBL6874599 | 0.83 | KLK5 (0.48) | CTSKCTSSATMAKT1CTSL | |
| SCHEMBL10463737 | 0.81 | CTSK (0.43) | MAPTCTSKCTSSATMCTSL | |
| SCHEMBL8911849 | 0.81 | CTSK (0.43) | MAPTCTSKCTSSATMAKT1 | |
| SCHEMBL8911855 | 0.79 | CTSK (0.41) | MAPTCTSKCTSSATMALDH1A1 | |
| SCHEMBL8529888 | 0.78 | CTSK (0.44) | MAPTCTSKCTSSATMCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292921-A | Process for the enantioselective preparation of phenylisoserine derivatives | RHONE-POULENC RORER S.A. (FR) | 1994-03-08 | — | — | US | disclosed |
| US-5290957-A | Process for the stereoselective preparation of phenylisoserine derivatives used in making taxols | RHONE POULENC RORER S.A. (FR) | 1994-03-01 | — | — | US | disclosed |