Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CTSH | P09668 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31118308 | 0.86 | TPMT (0.47) | TPMTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL6599426 | 0.85 | TPMT (0.50) | TPMTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL11265430 | 0.82 | GPR35 (0.50) | TPMTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL6275780 | 0.81 | TSHR (0.50) | TPMTTDP1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL34473595 | 0.81 | TDP1 (0.47) | TPMTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL11983744 | 0.80 | ALDH1A1 (0.52) | TDP1TSHRSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL69641 | 0.80 | TPMT (0.49) | TPMTTDP1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL1896801 | 0.79 | TDP1 (0.56) | TDP1TSHRSMN1; SMN2GPR35ALDH1A1 | |
| SCHEMBL28047042 | 0.79 | TDP1 (0.47) | TPMTTDP1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6237101 | 0.79 | TSHR (0.49) | TDP1TSHRSMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101216468-B | 2-methoxymethyl-4-aminophenol and its impurity highly effective liquid phase chromatography analytical method | SHANGHAI CHEMICAL REAGENT RES INST | 2012-04-18 | — | — | CN | claimed |
| CN-101216468-A | 2-methoxymethyl-4-aminophenol and its impurity highly effective liquid phase chromatography analytical method | SHANGHAI CHEMICAL REAGENT RES (CN) | 2008-07-09 | — | — | CN | claimed |
| US-20030041392-A1 | Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same | Wella GmbH (DE) | 2003-03-06 | — | — | US | claimed |
| CN-101216468-B | 2-methoxymethyl-4-aminophenol and its impurity highly effective liquid phase chromatography analytical method | SHANGHAI CHEMICAL REAGENT RES INST | 2012-04-18 | — | — | CN | disclosed |
| CN-101216468-A | 2-methoxymethyl-4-aminophenol and its impurity highly effective liquid phase chromatography analytical method | SHANGHAI CHEMICAL REAGENT RES (CN) | 2008-07-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030041392-A1 | Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same | KRT18, SCNN1B, DDAH1 | TPMT 1341/4885TDP1 1142/4885TSHR 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.