Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.43 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218362 | 0.84 | DPP8 (0.41) | DPP8DPP7ANPEPDPP9DPP4 | |
| SCHEMBL7226623 | 0.83 | METAP2 (0.39) | DPP8DPP7ANPEPDPP9LTA4H | |
| SCHEMBL7428900 | 0.82 | SLC1A1 (0.48) | DPP8DPP7ANPEPDPP9DPP4 | |
| SCHEMBL7911821 | 0.82 | ALDH1A1 (0.38) | DPP8DPP7ANPEPRNPEPDNPEP | |
| SCHEMBL7908670 | 0.80 | DPP8 (0.35) | DPP8DPP7ANPEPDPP9DPP4 | |
| SCHEMBL7219248 | 0.76 | FOLH1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL7975011 | 0.76 | DPP8 (0.53) | DPP8DPP7ANPEPDPP9DPP4 | |
| SCHEMBL7224578 | 0.76 | DPP7 (0.33) | DPP7 | |
| SCHEMBL7296595 | 0.75 | DPP8 (0.63) | DPP8DPP7ANPEPDPP9DPP4 | |
| SCHEMBL31134030 | 0.74 | DPP8 (0.68) | DPP8DPP7ANPEPDPP9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576780-B1 | Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors | GD SEARLE & COMPANY | 2003-06-10 | — | — | US | disclosed |
| US-6207708-B1 | FOR THERAPY AND PROPHYLAXIS OF AUTOIMMUNE AND/OR INFLAMMATORY CONDITIONS AFFECTING THE JOINTS SUCH AS ARTHRITIS, AND INFLAMMATORY BOWEL DISEASE, CARDIVASCULAR ISCHEMIA, DIABETES, CONGESTIVE HEART FAILURE, MYOCARDITIS, ATHEROSCLEROSIS, | G. D. SEARLE & COMPANY | 2001-03-27 | — | — | US | disclosed |
| EP-0885188-B1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2000-09-27 | — | — | EP | disclosed |