Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130387 | 0.86 | NPC1 (0.39) | HPGDSMN1; SMN2ALDH1A1TDP1HRH1 | |
| SCHEMBL6513679 | 0.85 | HPGD (0.42) | HPGDSMN1; SMN2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6513683 | 0.85 | HPGD (0.42) | HPGDSMN1; SMN2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27634125 | 0.80 | ALDH1A1 (0.60) | HPGDSMN1; SMN2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL27446682 | 0.80 | TSHR (0.53) | HPGDSMN1; SMN2ALDH1A1TDP1TSHR | |
| Fluoride SCHEMBL27378143 | 0.79 | TSHR (0.51) | HPGDSMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL3476385 | 0.79 | HTR2A (0.41) | HPGDSMN1; SMN2ALDH1A1TDP1LMNA | |
| SCHEMBL16241188 | 0.79 | GPR35 (0.51) | HPGDALDH1A1TDP1CYP3A4 | |
| SCHEMBL7628294 | 0.77 | ERN1 (0.42) | SMN1; SMN2ALDH1A1TDP1TSHRNPC1 | |
| SCHEMBL7628291 | 0.76 | TSHR (0.44) | HPGDALDH1A1TDP1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596734-B1 | Method for stimulating, regulating and modulating metabolism of fats in adipose tissue in mammals, comprising administering to a mammal an effective amount of a beta 3- adrenoreceptor agonist | MOLECULAR DESIGN INTERNATIONAL, INC. | 2003-07-22 | — | — | US | disclosed |