Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MGMT | P16455 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278461 | 0.88 | TDP1 (0.42) | MAPTMGMTLMNAALDH1A1TDP1 | |
| SCHEMBL6155901 | 0.82 | MAPT (0.40) | MAPTHTTMGMTLMNAALDH1A1 | |
| SCHEMBL27634125 | 0.81 | ALDH1A1 (0.60) | MAPTHTTLMNAALDH1A1TDP1 | |
| SCHEMBL27446682 | 0.81 | TSHR (0.53) | ALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL11788910 | 0.81 | CYP19A1 (0.39) | MAPTHTTMGMTLMNAALDH1A1 | |
| Fluoride SCHEMBL27378143 | 0.80 | TSHR (0.51) | ALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL16241188 | 0.80 | GPR35 (0.51) | ALDH1A1TDP1HPGDMEN1KMT2A | |
| SCHEMBL8564450 | 0.80 | MAPT (0.41) | MAPTHTTMGMTLMNAALDH1A1 | |
| SCHEMBL7628294 | 0.79 | ERN1 (0.42) | HTR2AMAPTHTTLMNAALDH1A1 | |
| SCHEMBL7219340 | 0.79 | HPGD (0.41) | LMNAALDH1A1TDP1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097815-A2 | A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | disclosed |