Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674146 | 0.88 | ALDH1A1 (0.44) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL10409152 | 0.82 | HIF1A (0.56) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL7212848 | 0.82 | THRB (0.43) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL10606162 | 0.80 | ALDH1A1 (0.41) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL14173150 | 0.76 | ELANE (0.36) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL11043033 | 0.75 | THRB (0.36) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL672151 | 0.75 | ALDH1A1 (0.43) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL3411706 | 0.74 | THRB (0.47) | ALDH1A1CYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL11997925 | 0.73 | THRB (0.43) | ALDH1A1ALOX15ALOX12CYP3A4HPGD | |
| SCHEMBL6939287 | 0.72 | HSD17B10 (0.50) | ALDH1A1ALOX15ALOX12CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624236-B1 | Sol-gel-condensable cyclosiloxane(meth) acrylates; dentistry | 3M ESPE AG (DE) | 2003-09-23 | — | — | US | disclosed |
| EP-1141094-B1 | CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS | 3M ESPE AG (DE) | 2002-07-24 | — | — | EP | disclosed |