SCHEMBL674146

SCHEMBL674146

C=C(C)C(=O)Oc1c(Br)cc(C(C)(C)c2cc(Br)c(OC(=O)C(=C)C)c(Br)c2)cc1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 3/20 0.44
ALOX15 P16050 2/20 0.44
ALOX12 P18054 2/20 0.44
HPGD P15428 2/20 0.44
TSHR P16473 2/20 0.44
HIF1A Q16665 2/20 0.44
CYP3A4 P08684 1/20 0.44
CASP1 P29466 1/20 0.44
RECQL P46063 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CHEK1 O14757 1/20 0.39
DAPK3 O43293 1/20 0.39
RET P07949 1/20 0.39
PDGFRB P09619 1/20 0.39
PIM1 P11309 1/20 0.39
PDGFRA P16234 1/20 0.39
KDR P35968 1/20 0.39
MAPK8 P45983 1/20 0.39
RPS6KA3 P51812 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10409152 0.94 HIF1A (0.56) ALDH1A1HSD17B10ALOX15ALOX12HPGD
SCHEMBL7219368 0.88 ALDH1A1 (0.35) ALDH1A1HSD17B10ALOX15ALOX12HPGD
SCHEMBL10606162 0.88 ALDH1A1 (0.41) ALDH1A1HSD17B10ALOX15ALOX12HPGD
SCHEMBL14173150 0.83 ELANE (0.36) ALDH1A1HSD17B10ALOX15ALOX12HPGD
SCHEMBL297222 0.82 HSD17B10 (0.44) ALDH1A1HSD17B10ALOX15ALOX12HPGD
SCHEMBL6939287 0.82 HSD17B10 (0.50) ALDH1A1HSD17B10ALOX15ALOX12HPGD
SCHEMBL10886229 0.81 HSD17B10 (0.42) ALDH1A1HSD17B10ALOX15ALOX12HPGD
SCHEMBL14173154 0.80 ELANE (0.34) ALDH1A1ELANEKMT2AATMMAPT
SCHEMBL11043033 0.80 THRB (0.36) ALDH1A1HSD17B10ALOX15ALOX12HPGD
SCHEMBL1837592 0.80 HSD17B10 (0.37) ALDH1A1HSD17B10ALOX15ALOX12ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
CN-115677458-B Method for improving stereoselectivity of catalytic bromination addition reaction 山东省海洋化工科学研究院 2024-04-12 CN claimed
WO-2023078367-A1 SECONDARY BATTERY 珠海冠宇电池股份有限公司 2023-05-11 WO claimed
CN-115677458-A Method for improving stereoselectivity of catalytic bromination addition reaction 山东省海洋化工科学研究院 2023-02-03 CN claimed
CN-114094102-A Secondary battery 珠海冠宇电池股份有限公司 2022-02-25 CN claimed
EP-1834975-B1 Thermosetting poly(phenylene ether) SABIC INNOVATIVE PLASTICS IP (NL) 2011-05-11 EP claimed
EP-1856196-B1 PROTECTED POLYCARBONATE FILMS HAVING THERMAL AND UV RADIATION STABILITY, AND METHOD OF MAKING SABIC INNOVATIVE PLASTICS IP (NL) 2009-07-15 EP claimed
EP-1834975-A1 Poly(Phenylene ether) - Polyvinyl thermosetting resin General Electric Company (US) 2007-09-19 EP claimed
US-6617398-B2 Forming laminate; curing; cladding with copper; printed circuits GENERAL ELECTRIC COMPANY 2003-09-09 US claimed
US-20020028337-A1 Poly (phenylene ether) - polyvinyl thermosetting resin SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-03-07 US claimed
US-6352782-B2 REACTING A POLYPHENYLENE ETHER CONTAINING HYDROXY GROUPS THAT HAVE BEEN CAPPED WITH A COMPOUND CONTAINING ETHYLENICALLY UNSATURATION WITH A CURABLE UNSATURATED MONOMER CAPABLE OF REACTING WITH ETHYLENICALLY UNSATURATED COMPOUND GENERAL ELECTRIC COMPANY 2002-03-05 US claimed
US-6352782-B1 None US disclosed
JP-4180904-A None JP disclosed
JP-63207836-A None JP disclosed
CN-115677458-B Method for improving stereoselectivity of catalytic bromination addition reaction 山东省海洋化工科学研究院 2024-04-12 CN disclosed
US-4988274-A Method and apparatus for producing an optical element DRESSER INDUSTRIES, INC. (US) 1991-01-29 US disclosed
US-4975223-A Copolymer of 4-isopropenylbiphenyl and monofunctional aromatic monomers; high refractive index KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-12-04 US disclosed
US-4931523-A HIGH DYEABILITY, REFRACTIVE INDEX KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-06-05 US disclosed
EP-0322614-A2 Optical material KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-07-05 EP disclosed
JP-S63207836-A FLAME-RETARDANT THERMOSETTING RESIN COMPOSITION HITACHI CHEM CO LTD 1988-08-29 JP disclosed