Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13350337 | 0.82 | FABP3 (0.42) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL12545564 | 0.78 | TRPA1 (0.52) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL29469912 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL17093011 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL1805043 | 0.76 | ALDH1A1 (0.40) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL14200039 | 0.76 | ALDH1A1 (0.40) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL13947629 | 0.76 | CA1 (0.49) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL1805045 | 0.76 | ALDH1A1 (0.40) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL23598883 | 0.76 | CA2 (0.49) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL22606257 | 0.76 | APEX1 (0.47) | GAACA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331221-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES FOR THEIR PREPARATION | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-07-30 | — | — | EP | disclosed |