Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21923501 | 0.79 | MLYCD (0.70) | KMT2AMEN1HDAC6HDAC1RAB9A | |
| SCHEMBL7217357 | 0.73 | LMNA (0.64) | KMT2AMEN1HDAC6HDAC3RAB9A | |
| SCHEMBL7219598 | 0.73 | GLRA3 (0.39) | KMT2ARAB9ANPC1ALDH1A1NR1H4 | |
| SCHEMBL10350353 | 0.73 | ALOX5 (0.48) | RAB9ANPC1ALDH1A1HSP90AA1 | |
| SCHEMBL1003665 | 0.72 | KMT2A (0.83) | KMT2AMEN1HDAC6HDAC1RAB9A | |
| SCHEMBL180384 | 0.71 | NPC1 (0.73) | KMT2AMEN1RAB9ARIPK1HPGD | |
| SCHEMBL16597337 | 0.71 | KMT2A (0.59) | KMT2AMEN1HDAC4HDAC6HDAC3 | |
| SCHEMBL12265785 | 0.71 | RIPK1 (0.72) | KMT2AMEN1RAB9ARIPK1HPGD | |
| SCHEMBL23528960 | 0.70 | CYP2C19 (0.48) | KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL1690506 | 0.70 | KMT2A (0.75) | KMT2AMEN1HDAC6HDAC1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |