Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.75 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.75 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943349 | 1.00 | OXTR (0.75) | OXTRAVPR1AAVPR2FFAR2MAPK1 | |
| SCHEMBL5742342 | 0.92 | OXTR (0.71) | OXTRAVPR1AMAPK1ROCK2ROCK1 | |
| SCHEMBL5743780 | 0.86 | OXTR (1.00) | OXTRAVPR1AAVPR2FFAR2ROCK2 | |
| SCHEMBL4943198 | 0.86 | OXTR (1.00) | OXTRAVPR1AAVPR2FFAR2ROCK2 | |
| SCHEMBL4936543 | 0.86 | OXTR (1.00) | OXTRAVPR1AAVPR2FFAR2ROCK2 | |
| SCHEMBL4940385 | 0.86 | OXTR (1.00) | OXTRAVPR1AAVPR2FFAR2ROCK2 | |
| SCHEMBL4936354 | 0.86 | OXTR (1.00) | OXTRAVPR1AAVPR2FFAR2ROCK2 | |
| SCHEMBL4936174 | 0.86 | OXTR (1.00) | OXTRAVPR1AAVPR2FFAR2ROCK2 | |
| SCHEMBL4942975 | 0.86 | OXTR (1.00) | OXTRAVPR1AAVPR2FFAR2ROCK2 | |
| SCHEMBL5743785 | 0.86 | OXTR (1.00) | OXTRAVPR1AAVPR2FFAR2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171309-A1 | Pharmaceutically active pyrrolidine derivatives as bax inhibitors | MERCK SERONO SA (CH) | 2003-09-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171309-A1 | Pharmaceutically active pyrrolidine derivatives as bax inhibitors | SUCNR1, PYCR1, GLS | OXTR 189/4885AVPR1A 1456/4885AVPR2 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.