Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220067 | 0.82 | MAPK1 (0.39) | CCNCCDK8KDM4ECYP2A6LMNA | |
| SCHEMBL7215525 | 0.79 | ALDH1A1 (0.41) | KDM4ELMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL10058048 | 0.74 | MEN1 (0.38) | CCNCCDK8KDM4ECYP2A6LMNA | |
| SCHEMBL7215529 | 0.74 | KDM5A (0.39) | CCNCCDK8KDM4ECYP2A6LMNA | |
| SCHEMBL457019 | 0.73 | CYP2A6 (0.34) | KDM4ECYP2A6LMNAALDH1A1HSD17B10 | |
| SCHEMBL9712661 | 0.73 | GABRA1 (0.48) | PDE9AKDM4ECYP2A6LMNAALDH1A1 | |
| SCHEMBL19779742 | 0.73 | CYP2E1 (0.37) | CCNCCDK8KDM4ECYP2A6ALDH1A1 | |
| SCHEMBL7975202 | 0.72 | CYP2A6 (0.42) | PDE9AKDM4ECYP2A6LMNAALDH1A1 | |
| SCHEMBL16883661 | 0.71 | KDM4E (0.41) | KDM4ECYP2A6LMNAALDH1A1HSD17B10 | |
| SCHEMBL2154515 | 0.71 | CYP2A6 (0.43) | KDM4ECYP2A6LMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |