Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.40 |
| ▸ | CTSK | P43235 | 9/20 | 0.36 |
| ▸ | CTSS | P25774 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213412 | 0.86 | AR (0.42) | ARMAPK1KDM4EHSD17B10TSHR | |
| SCHEMBL7219021 | 0.86 | AR (0.37) | ARCTSKCTSSKDM4EHSD17B10 | |
| SCHEMBL19771880 | 0.82 | CTSK (0.40) | ARCTSKCTSSMAPK1KDM4E | |
| SCHEMBL11401162 | 0.82 | CHEK1 (0.38) | ARCTSKMAPK1KDM4EHSD17B10 | |
| SCHEMBL24135362 | 0.81 | PGK1 (0.37) | ARCTSKCTSSMAPK1KDM4E | |
| SCHEMBL25537805 | 0.80 | CTSK (0.41) | ARCTSKCTSSKDM4EHSD17B10 | |
| SCHEMBL7213409 | 0.78 | MAPK1 (0.39) | ARMAPK1KDM4EHSD17B10TSHR | |
| SCHEMBL23832142 | 0.77 | AR (0.39) | ARCTSKCTSSKDM4EHSD17B10 | |
| SCHEMBL23832138 | 0.77 | PGK1 (0.44) | ARCTSKCTSSKDM4E | |
| SCHEMBL16389971 | 0.77 | KDM4E (0.39) | KDM4ETSHRLMNACYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |