Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | PDE9A | O76083 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220089 | 0.85 | NOS3 (0.36) | MAPK1ARPDE9AKDM5AMEN1 | |
| SCHEMBL2514335 | 0.84 | ALDH1A1 (0.38) | MAPK1ARPDE9APDE10AMBOAT4 | |
| SCHEMBL14872340 | 0.81 | AR (0.39) | MAPK1ARPDE9AKDM5AMEN1 | |
| SCHEMBL8081930 | 0.79 | MAPK1 (0.38) | MAPK1ARMEN1KMT2AL3MBTL1 | |
| SCHEMBL2202379 | 0.79 | MAPK1 (0.38) | MAPK1ARKDM5AMEN1KMT2A | |
| SCHEMBL23586637 | 0.79 | MAPK1 (0.38) | MAPK1ARMEN1KMT2AL3MBTL1 | |
| SCHEMBL26510896 | 0.79 | CYP11B1 (0.41) | MAPK1AR | |
| SCHEMBL15434726 | 0.79 | NOS3 (0.52) | MAPK1ARMEN1KMT2AL3MBTL1 | |
| SCHEMBL7219799 | 0.78 | AR (0.40) | MAPK1ARMEN1KMT2AL3MBTL1 | |
| SCHEMBL25786963 | 0.77 | MBOAT4 (0.37) | MAPK1ARPDE9AKDM5AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |