Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491066 | 0.80 | KDM4E (0.32) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1225214 | 0.78 | NFE2L2 (0.36) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL726410 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL719277 | 0.77 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28081292 | 0.77 | ALDH1A1 (0.32) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8196392 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8012068 | 0.74 | KDM4E (0.31) | KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3692221 | 0.74 | ALOX5AP (0.38) | — | |
| SCHEMBL2137791 | 0.72 | — | — | |
| SCHEMBL466380 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | claimed |
| EP-2396306-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2011-12-21 | — | — | EP | claimed |
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | claimed |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | disclosed |
| EP-2396306-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | DPYD, DHODH, TYMP | MAOA 547/4885KDM4E 2202/4885ALDH1A1 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.