SCHEMBL7219933

SCHEMBL7219933

Cc1c(Cc2ccccc2)n(COCCO)c(=O)[nH]c1=O

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
UPP1 Q16831 1/20 0.59
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PNP P00491 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5200095 0.85 UPP1 (0.60) UPP1ALDH1A1HPGDPNP
SCHEMBL12752135 0.83 ALDH1A1 (0.45) UPP1ALDH1A1HPGDMEN1KMT2A
SCHEMBL12752138 0.78 KMT2A (0.45) ALDH1A1HPGDMEN1KMT2A
SCHEMBL9598080 0.78 UPP1 (0.48) UPP1ALDH1A1HPGDMEN1KMT2A
Hept SCHEMBL384288 0.78 UPP1 (0.48) UPP1ALDH1A1HPGDMEN1KMT2A
SCHEMBL9357481 0.77 UPP1 (0.47) UPP1ALDH1A1HPGDKMT2A
SCHEMBL9357419 0.77 UPP1 (0.47) UPP1ALDH1A1HPGDMEN1KMT2A
SCHEMBL9357478 0.77 UPP1 (0.47) UPP1ALDH1A1HPGDKMT2A
SCHEMBL7558156 0.74 UPP1 (1.00) UPP1
SCHEMBL5199239 0.74 UPP1 (0.44) UPP1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37979-E1 Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof MITSUBISHI CHEMICAL CORPORATION 2003-02-04 US disclosed
EP-0829476-B1 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof MITSUBISHI CHEM CORP (JP) 2002-08-28 EP disclosed
EP-0829476-A2 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof Mitsubishi Chemical Corporation (JP) 1998-03-18 EP disclosed
US-5461060-A Antiretroviral activity MITSUBISHI KASEI CORPORATION (JP) 1995-10-24 US disclosed
EP-0420763-A2 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof Mitsubishi Chemical Corporation (JP) 1991-04-03 EP disclosed