Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 6/20 | 0.50 |
| ▸ | CDC25B | P30305 | 6/20 | 0.50 |
| ▸ | CDC25C | P30307 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25236336 | 0.98 | EPHX2 (0.73) | EPHX2ALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL8087417 | 0.91 | EPHX2 (0.83) | EPHX2ALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL3506260 | 0.91 | EPHX2 (0.83) | EPHX2ALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL14054041 | 0.91 | EPHX2 (0.83) | EPHX2ALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL29236924 | 0.91 | EPHX2 (0.83) | EPHX2ALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL2703694 | 0.91 | EPHX2 (0.83) | EPHX2ALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL31240243 | 0.90 | EPHX2 (0.81) | EPHX2ALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL29236858 | 0.90 | EPHX2 (0.81) | EPHX2ALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL9116093 | 0.87 | ALDH1A1 (0.56) | EPHX2ALDH1A1MAPTPKMHSD17B10 | |
| SCHEMBL17491872 | 0.84 | ALDH1A1 (0.66) | EPHX2ALDH1A1MAPTPKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6590119-B2 | Catalytic alcoholysis of benzoylcyclohexanone ketals; products useful as intermediates for diarylpyrrole therapeutic agents | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-07-08 | — | — | US | disclosed |
| US-20020107408-A1 | Methods for the synthesis of dioxoalkanoic acid compounds | FERRO MICHAEL P (US) | 2002-08-08 | — | — | US | disclosed |
| US-6355812-B1 | ALCOHOLYSIS OF BENZOYLCYCLOHEXANONE KETAL COMPOUNDS | ORTH-MCNEIL PHARMACEUTICAL, INC. | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107408-A1 | Methods for the synthesis of dioxoalkanoic acid compounds | DCK, DDT, AOX1 | EPHX2 287/4885ALDH1A1 281/4885MAPT 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.