Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057633 | 0.85 | POLB (0.59) | POLBKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL2828050 | 0.85 | KDM4E (0.54) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL11427185 | 0.77 | POLB (1.00) | POLBKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL7214687 | 0.76 | ALDH1A1 (0.56) | POLBKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL7214686 | 0.76 | ALDH1A1 (0.56) | POLBKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL7214682 | 0.76 | ALDH1A1 (0.56) | POLBKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL2827984 | 0.75 | ALDH1A1 (0.59) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL7214293 | 0.75 | KDM4E (0.53) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL7219643 | 0.74 | KDM4E (0.43) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL1988320 | 0.73 | ALDH1A1 (0.66) | KDM4ERAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |