SCHEMBL7220384

SCHEMBL7220384

COc1cc(NS(=O)(=O)N2CCCC[C@H]2C(=O)OCCCCc2ccccc2)cc(OC)c1OC

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 19/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7507953 1.00 FKBP1A (0.69) FKBP1A
SCHEMBL7227327 0.90 FKBP1A (0.68) FKBP1A
SCHEMBL7497141 0.90 FKBP1A (0.68) FKBP1A
SCHEMBL7220462 0.89 FKBP1A (0.58) FKBP1A
SCHEMBL7220468 0.89 FKBP1A (0.58) FKBP1A
SCHEMBL7506812 0.88 FKBP1A (0.59) FKBP1A
SCHEMBL7220517 0.88 FKBP1A (0.59) FKBP1A
SCHEMBL7226070 0.87 FKBP1A (0.53) FKBP1A
SCHEMBL7507997 0.87 FKBP1A (0.72) FKBP1A
SCHEMBL7228590 0.87 FKBP1A (0.72) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6544987-B2 Pyrrolidine or piperidine sulfonyl compounds; stimulate neurite outgrowth in nerve cells leading to nerve regeneration for treatment of hair loss, memory loss or vision disorders PFIZER INC. 2003-04-08 US disclosed
US-20020061881-A1 Compounds, compositions, and methods for stimulating neuronal growth and elongation AGOURON PHARMACEUTICALS, INC. 2002-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020061881-A1 Compounds, compositions, and methods for stimulating neuronal growth and elongation NGF, GAP43, BDNF FKBP1A 4192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.