Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7216324 | 0.90 | LTA4H (0.40) | KDM4EALDH1A1POLBUSP2TSHR | |
| SCHEMBL7214242 | 0.84 | LTA4H (0.36) | KMT2AALDH1A1POLBUSP2TSHR | |
| SCHEMBL3423830 | 0.80 | KDM4E (0.51) | PDE3BPDE3AMAOBKMT2AMEN1 | |
| SCHEMBL4318577 | 0.78 | PDE3B (0.49) | PDE3BPDE3AMAOBKMT2AMEN1 | |
| SCHEMBL5555614 | 0.78 | PDE3B (0.48) | PDE3BPDE3AMAOBKMT2AMEN1 | |
| SCHEMBL7450120 | 0.76 | PDE3B (0.41) | PDE3BPDE3AMAOBKMT2AMEN1 | |
| SCHEMBL7450125 | 0.71 | RAB9A (0.45) | PDE3BPDE3AKMT2AKDM4EALDH1A1 | |
| SCHEMBL7220431 | 0.71 | TSHR (0.49) | MAOBKMT2ACRHBPCRHR2MEN1 | |
| SCHEMBL23796493 | 0.71 | MEN1 (0.59) | MAOBKMT2AMEN1HSP90AA1ALDH1A1 | |
| SCHEMBL9321664 | 0.70 | MEN1 (0.52) | MAOBKMT2AMEN1HSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |