Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555614 | 0.88 | PDE3B (0.48) | KDM4EPDE3BPDE3AMAOBKMT2A | |
| SCHEMBL3420123 | 0.87 | ALDH1A1 (0.48) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL4318577 | 0.86 | PDE3B (0.49) | KDM4EPDE3BPDE3AMAOBKMT2A | |
| SCHEMBL5277715 | 0.81 | ALDH1A1 (0.43) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL23796493 | 0.80 | MEN1 (0.59) | MAOBKMT2AMEN1HSP90AA1ALDH1A1 | |
| SCHEMBL7220436 | 0.80 | PDE3B (0.41) | KDM4EPDE3BPDE3AMAOBKMT2A | |
| SCHEMBL20111506 | 0.79 | ALDH1A1 (0.51) | KDM4EGLAATMPDE3BPDE3A | |
| SCHEMBL13367226 | 0.79 | KDM4E (0.56) | KDM4EGLAATMKMT2AMEN1 | |
| SCHEMBL9321664 | 0.79 | MEN1 (0.52) | KDM4EMAOBKMT2AMEN1HSP90AA1 | |
| SCHEMBL7450120 | 0.79 | PDE3B (0.41) | KDM4EPDE3BPDE3AMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453652-B2 | Di-macrocycles | LUMIPHORE, INC. (US) | 2022-09-27 | — | — | US | disclosed |
| EP-2920157-B1 | DI-MACROCYCLES | LUMIPHORE INC (US) | 2019-09-11 | — | — | EP | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| EP-2920157-A1 | DI-MACROCYCLES | Lumiphore, Inc. (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014078690-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |
| WO-2009154870-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2009-12-23 | — | — | WO | disclosed |
| WO-2009154870-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2009-12-23 | — | — | WO | disclosed |
| US-20060292079-A1 | Conjugates of hydroxypyridinone derivative metal complexes with biomolecules and their use for MRI diagnosis | EPIX PHARMACEUTICALS, INC. | 2006-12-28 | — | — | US | disclosed |
| US-6846915-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-25 | — | — | US | disclosed |
| US-20050008570-A1 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-13 | — | — | US | disclosed |
| EP-1423399-A2 | HYDROXYPYRIDONATE AND HYDROXYPYRIMIDINONE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-06-02 | — | — | EP | disclosed |
| US-6610692-B1 | Anticoagulants | MERCK & CO., INC. | 2003-08-26 | — | — | US | disclosed |
| US-20030095922-A1 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-05-22 | — | — | US | disclosed |
| WO-2003016923-A2 | HYDROXYPYRIDONATE AND HYDROXYPYRIMIDINONE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-02-27 | — | — | WO | disclosed |
| EP-1124822-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1124822-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026211-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050008570-A1 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | HAMP, GDI1, MPI | KDM4E 732/4885GLA 2058/4885ATM 4840/4885 |
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | KDM4E 4621/4885GLA 3982/4885ATM 2804/4885 |
| US-11453652-B2 | Di-macrocycles | DLD, NDC1, MCL1 | KDM4E 4621/4885GLA 3982/4885ATM 2804/4885 |
| US-20060292079-A1 | Conjugates of hydroxypyridinone derivative metal complexes with biomolecules and their use for MRI diagnosis | KLK3, HPGD, HAMP | KDM4E 1907/4885GLA 3411/4885ATM 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.